Pipeline

From preclinical promise toward the clinic

Our lead program, SymphNode, is in preclinical development for solid tumors. Active programs and potential future applications are shown separately below.

Development pipeline

Program
DiscoveryPreclinicalIND-enablingPhase 1Phase 2–3
Active development
SymphNode Triple-negative breast cancer Preclinical
SymphNode Melanoma Preclinical
Potential future applications
Additional solid tumors Platform expansion Potential
Combination regimens With complementary immune-based treatments Potential

Solid bars show programs in active development. Dashed bars show potential applications of the platform that are not yet in active development.

Where we are

Lead program status

Preclinical evidence

Promising antitumor activity in preclinical cancer models, including evidence of improved survival and reduced metastatic tumor growth.

Current work

Advancing preclinical evaluation, safety testing, and manufacturing development to support future clinical translation.

Non-dilutive support

Funded by the NIH’s National Cancer Institute through a Fast-Track Phase II SBIR award.

Investigational technology. SymphNode remains investigational and is not an approved cancer treatment. It has not been evaluated in human clinical trials, and its safety and efficacy have not been established.